Cellular SPR Group

List of Publications

2011

•	Baumgarten, S.; Robelek, R. Surface Plasmon Resonance (SPR) Sensors for the rapid, sensitive detection of the cellular response to osmotic stress. Sensors and Actuators B, in press, doi:10.1016/j.snb.2011.02.041

2010

•	Robelek, R.; Wegener, J. Label-free and Time-Resolved Measurements of Cell Volume Changes by Surface Plasmon Resonance (SPR) Spectroscopy. Biosensors & Bioelectronics 2010, 25 (5), 1221-1224.

2008

•	Leutenegger, M.; Lasser, T.; Sinner, E.K.; Robelek, R. Imaging of G protein-coupled receptors in solid-supported planar lipid membranes. Biointerphases 2008, 3 (2), FA136-FA145.
•	Marki, I.; Leutenegger, M.; Geissbühler, M.; Robelek, R.; Sinner, E.K.; Lasser, T. Imaging of G protein-coupled receptors in solid-supported planar membranes at the single molecule level. Single Molecule Spectroscopy and Imaging 2008, 6862 (34), 68620X.

2007

•	Robelek R.; Leutenegger M.; Wiltschi B.; Lemker E.S.; Oesterhelt D.; Lasser T.; Sinner E.K. In vitro synthesis of GPCRs in a solid supported planar lipid membrane system. Biophys. J. 2007, 38A Suppl. S
•	Robelek, R.; Lemker, E.; Wiltschi, B.; Kirste, V.; Naumann, R.; Oesterhelt, D.; Sinner, E.K. Incorporation of in vitro Synthesized GPCRs into a Tethered Artificial Lipid Membran System. Angew. Chem. Intl. Ed 2007, 46; 605-608.

2006

•	Robelek, R.; Stefani, F., Knoll, W. Oligonucleotide Hybridization Monitored by Surface Plasmon Enhanced Fluorescence Spectroscopy with Bio-Conjugated Core/Shell Quantum Dots. Influence of Luminescence Blinking. Phys. Stat. Sol. (a) 2006, 203(14); 3468-3475.
•	Knoll, W.; Zong, X.; Stefani, F.; Robelek, R.; Niu, L.; Rochholz, H.; Shumaker-Parry, J; Kreiter, M. Optics with Nano-Sized Structures Made from Semiconductors and (Noble) Metals. JNOPM 2006, 15(3), 355-367.

2005

•	Su, X.; Wu, Y-J.; Robelek, R., Knoll, W. Surface Plasmon Resonance Spectroscopy and Quartz Crystal Microbalance Study of Streptavidin Film Structure Effects on Biotinylated DNA Assembly and Target DNA Hybridization. Langmuir 2005, 21(1); 348-53.
•	Su, X.; Wu, Y-J.; Robelek, R.; Knoll, W. Surface Plasmon Resonance Spectroscopy and Quartz Crystal Microbalance Study of MutS Binding with Single Thymine-Guanine Mismatched DNA. Front. Biosci. 2005, 10; 268-274.

2004

•	Bonin, I.; Robelek, R.; Benecke, H.; Urlaub, H.; Bacher, A.; Richter, G.; Wahl, M.C. Crystal Structures of NusB from Thermotoga maritima and Implications for RNA Binding. Biochem J. 2004, 383(3); 419-28.
•	Robelek, R.; Niu, L.; Schmid, E.L.; Knoll, W. Multiplexed Hybridization Detection of Quantum Dot Conjugated DNA Sequences using Surface Plasmon Enhanced Fluorescence Microscopy and Spectrometry. Anal. Chem. 2004, 76(20); 6160-6165.
•	Knoll, W.; Tamada, K.; Yu, F.; Robelek, R.; Niu, L.; Yao, D.; Han, M.; Zhong, X.; Schmid, E.L. Supramolecular interfacial architecture for biosensing. Polymeric Materials Science and Engineering 2004, 90; 687-688.
•	Knoll, W.; Han, M-Y.; Li, X.; Fernandez-Lopez, J-L.; Manna, A.; Müllen, K.; Nakamura, F.; Niu, L.; Robelek, R.; Schmid, E.L.; Tamada, K.; Zhong, X. Nanoscopic Building Blocks from Polymers, Metals, and Semiconductors for Hybrid Architectures. JNOPM. 2004, 13(2); 229ff.
•	Su, X.; Robelek, R.; Wu, Y.; Wang, G.; Knoll W. Detection of Point Mutation and Insertion Mutations in DNA using Quartz Crystal Microbalance and MutS, a Mismatch Binding Protein. Anal. Chem. 2004, 76(2); 489-494.

2003

•	Robelek, R.; Mühlberger, R.; Eisenreich, W.; Ettenhuber, C.; Sinner, E.-K.; Kessler, H.; Bacher, A. and Richter, G. RNA DNA discrimination by the antitermination protein NusB. J. Mol. Biol. 2003, 327, 973-83.

2002

•	Lüttgen, H.; Robelek, R.; Mühlberger, R.; Diercks, T.; Schuster, S. C.; Köhler, P., Kessler, H.; Bacher, A.; Richter, G. Transcriptional regulation by antitermination. Interaction of RNA with NusB protein and NusB/NusE protein complex of Escherichia coli. J. Mol. Biol. 2002, 316, 873-883.

Reviews and Book Chapter

•	Michaelis, S.; Robelek, R.; Wegener, J. Studying Cell-Surface Interactions In Vitro: A Survey about Experimental Approaches and Techniques. In Tissue Engineering III, Advances in Biochemical Engineering / Biotechnology., submitted
•	Robelek, R. Surface Plasmon Resonance Sensors in Cell Biology: Basics and Applications. Bioanal. Rev., 2009, 1(1), 57-72.
•	Knoll, W.; Kasry, A.; Liu. J.; Neumann, T.; Niu, L.; Park, H.; Paulsen, H.; Robelek, R.; Yu, F. Surface Plasmon Fluorescence Techniques for Bioaffnity Studies. In Handbook of Surface Plasmon Resonance (Chapter 9), Royal Society of Chemistry; ISBN: 978-0854042678.

Academic Works

•	Robelek, R. Studies of transcriptional antitermination in Escherichia coli. PhD Thesis, 2002, Technical University Munich.
•	Robelek, R. Untersuchungen zur Antitermination in Escherichia coli. Diploma Thesis, 1999, Technical University Munich.

List of Patents

•	Robelek, R.; Lempker, E.; Wiltschi; Sinner, E.K. Cell-free in vitro transcription and translation of membrane proteins into tethered lipid layers. 2006, European Patent PCT/EP06/008318.
•	Su, X.; Robelek, R.; Knoll, W.; O’Shea, S. Piezoelectric quartz crystal microbalance and method for high-throughput detection of genetic polymorphisms associated with diseases. 2005, US Patent Publication, Patent# US 2005164236.
•	Su, X.; Robelek, R.; Knoll, W.; O’Shea, S. Device and Method of Detecting Mutations and Polymorphisms in DNA. 2005, SG Patent Publication, Patent# SG 110153A.